產(chǎn)品名稱 |
pB3.1 |
商品貨號(hào) |
B213780 |
Designations |
pB3.1 |
Species |
Homo sapiens, human |
Applications |
This probe may be useful in studying diseases associated with the nerve growth factor receptor (NGFR). |
Vector |
Construct size (kb): 5.400000095367432 |
Insert |
DNA: genomic Insert lengths(kb): 1.100000023841858 Gene product: solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) [EPB3] Alleles: A1, A1, A2, A2 |
Insert Size (kb) |
1.100 |
Biosafety Level |
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
Shipping Information |
Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug) |
Comments |
The insert contains an internal PstI site. Restriction digests of the clone give the following sizes (kb): EcoRI--5.8; HindIII--5.5, 0.3; PstI--3.5, 2.1; BamHI--4.4, 1.1. EPB3 is tightly linked (LOD score = 11.40) to the NGFR (nerve growth factor receptor) gene in 23 CEPH informative families. This probe may be useful in studying diseases associated with the nerve growth factor receptor (NGFR). |
References |
Stewart EA, et al. A PstI polymorphism for the human erythrocyte surface protein band 3 (EPB3) demonstrates close linkage of EPB3 to the nerve growth factor receptor. Genomics 5: 633-635, 1989. PubMed: 2575590
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